The following articles (labelled with PubMed ID or TBD) are for your review| PMID | Article Title | Published | Deposition |
|---|
| 32712435 |
From irreversible to reversible covalent inhibitors: Harnessing the andrographolide scaffold for anti-inflammatory action. |
15-OCT-2020 |
30-MAR-2022 |
| 31422225 |
Galloyl esters of trans-stilbenes are inhibitors of FASN with anticancer activity on non-small cell lung cancer cells. |
15-NOV-2019 |
25-FEB-2021 |
| 31278031 |
Styryl quinazolinones and its ethynyl derivatives induce myeloid differentiation. |
15-AUG-2019 |
23-FEB-2021 |
| 31627059 |
Discovery of a potent histone deacetylase (HDAC) 3/6 selective dual inhibitor. |
15-DEC-2019 |
18-FEB-2021 |
| 26631440 |
Phenolic group on A-ring is key for dracoflavan B as a selective noncompetitive inhibitor of ?-amylase. |
15-DEC-2015 |
04-SEP-2020 |
| 24518296 |
Discovery of simplified N²-substituted pyrazolo[3,4-d]pyrimidine derivatives as novel adenosine receptor antagonists: efficient synthetic approaches, biological evaluations and molecular docking studies. |
01-MAR-2014 |
02-SEP-2020 |
| 14643890 |
Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione. |
XX-FEB-2004 |
30-AUG-2020 |
| 9703467 |
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists. |
13-AUG-1998 |
21-AUG-2020 |
| 30243158 |
Design and synthesis of potent dual inhibitors of JAK2 and HDAC based on fusing the pharmacophores of XL019 and vorinostat. |
05-OCT-2018 |
18-AUG-2020 |
| 29945795 |
Merging of ruxolitinib and vorinostat leads to highly potent inhibitors of JAK2 and histone deacetylase 6 (HDAC6). |
15-AUG-2018 |
17-AUG-2020 |
| 29545103 |
Design and synthesis of triple inhibitors of janus kinase (JAK), histone deacetylase (HDAC) and Heat Shock Protein 90 (HSP90). |
01-MAY-2018 |
17-AUG-2020 |
| 29274493 |
1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity. |
20-JAN-2018 |
28-JUL-2020 |
| 28953386 |
Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat. |
26-OCT-2017 |
20-NOV-2019 |
| 28177228 |
Design, Synthesis, and Biological Evaluation of Coupled Bioactive Scaffolds as Potential Anticancer Agents for Dual Targeting of Dihydrofolate Reductase and Thioredoxin Reductase. |
09-MAR-2017 |
16-JUL-2019 |
| 27541357 |
Design and Synthesis of Janus Kinase 2 (JAK2) and Histone Deacetlyase (HDAC) Bispecific Inhibitors Based on Pacritinib and Evidence of Dual Pathway Inhibition in Hematological Cell Lines. |
22-SEP-2016 |
07-SEP-2018 |
| 26994844 |
Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity. |
16-APR-2016 |
27-JUL-2017 |
| 22511346 |
Interaction of lapatinib with cytochrome P450 3A5. |
21-JUN-2012 |
08-MAY-2016 |
| 25615020 |
Specificity and inhibitory mechanism of andrographolide and its analogues as antiasthma agents on NF-¿B p50. |
27-FEB-2015 |
04-MAY-2016 |
| 25633494 |
A facile and novel synthesis of N(2)-, C(6)-substituted pyrazolo[3,4-d]pyrimidine-4 carboxylate derivatives as adenosine receptor antagonists. |
20-FEB-2015 |
22-APR-2016 |
| 25549554 |
Functionalized tetrahydro-1H-pyrido[4,3-b]indoles: a novel chemotype with Sirtuin 2 inhibitory activity. |
20-FEB-2015 |
20-APR-2016 |
| 24686016 |
Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II. |
14-APR-2014 |
07-FEB-2015 |
| 24177367 |
Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors. |
09-DEC-2013 |
25-JUL-2014 |
| 24080463 |
Restraining the flexibility of the central linker in terameprocol results in constrained analogs with improved growth inhibitory activity. |
18-OCT-2013 |
13-APR-2014 |
| 23688695 |
Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase. |
22-JUL-2013 |
13-APR-2014 |
| 23871912 |
A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities. |
09-SEP-2013 |
13-APR-2014 |
| 23514631 |
Functionalized indoleamines as potent, drug-like inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt). |
04-JUN-2013 |
12-APR-2014 |
| 24070012 |
Small molecule probe suitable for in situ profiling and inhibition of protein disulfide isomerase. |
15-NOV-2013 |
20-FEB-2014 |
| 17157012 |
Quantitative structure-activity relationship (QSAR) of indoloacetamides as inhibitors of human isoprenylcysteine carboxyl methyltransferase. |
05-FEB-2007 |
21-MAY-2013 |
| 20036565 |
Antifolate and antiproliferative activity of 6,8,10-triazaspiro[4.5]deca-6,8-dienes and 1,3,5-triazaspiro[5.5]undeca-1,3-dienes. |
03-FEB-2010 |
08-JAN-2013 |
| 19716698 |
Synthesis and in vitro evaluation of 2,4-diamino-1,3,5-triazine derivatives as neuronal voltage-gated sodium channel blockers. |
14-SEP-2009 |
26-DEC-2012 |
| 21908194 |
Does the combination of optimal substitutions at the C²-, N¿?¿- and N¿?¿-positions of the pyrazolo-triazolo-pyrimidine scaffold guarantee selective modulation of the human A3 adenosine receptors? |
29-SEP-2011 |
24-MAR-2012 |
| 21511471 |
Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. |
02-MAY-2011 |
04-DEC-2011 |
| 19703036 |
Antiproliferative activity against MCF-7 breast cancer cells by diamino-triazaspirodiene antifolates. |
XX-SEP-2009 |
28-NOV-2011 |
| 20809634 |
Amino derivatives of indole as potent inhibitors of isoprenylcysteine carboxyl methyltransferase. |
07-OCT-2010 |
12-JUN-2011 |
| 20304654 |
Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process. |
05-APR-2010 |
18-NOV-2010 |
| 20307065 |
The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition. |
15-APR-2010 |
18-NOV-2010 |
| 19328682 |
Expedient solid-phase synthesis of both symmetric and asymmetric diol libraries targeting aspartic proteases. |
13-JUL-2009 |
27-AUG-2010 |
| 19469544 |
Synthesis and evaluation of sphingosine analogues as inhibitors of sphingosine kinases. |
18-JUN-2009 |
11-JAN-2010 |
| 9834152 |
Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade. |
18-FEB-1999 |
11-JAN-2010 |
| 18800771 |
Novel opioid peptide derived antagonists containing (2S)-2-methyl-3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid [(2S)-Mdcp]. |
19-SEP-2008 |
11-JAN-2010 |
| 16913729 |
Replacement of the N-terminal tyrosine residue in opioid peptides with 3-(2,6-dimethyl-4-carbamoylphenyl)propanoic acid (Dcp) results in novel opioid antagonists. |
17-AUG-2006 |
10-NOV-2009 |
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